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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Cement (bone cement, kyphoplasty, vertebroplasty)
5
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Hemopericardium - Bloody pericardial effusion
1
Last update :
13/03/2019
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
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Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Vertebroplasty (kyphoplasty)
Publications
Fatal cardiac perforation and pulmonary embolism of leaked cement after percutaneous vertebroplasty.