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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cement (bone cement, kyphoplasty, vertebroplasty)

5

XV.ai Path: Acrylate bone cement pulmonary embolism

2
Last update : 09/07/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Vertebroplasty (kyphoplasty)
4

Publications

Pulmonary cement embolism is not associated with the cause of death in a post-mortem cohort of cement-augmented interventions in the spine.
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 2018 Oct;27;2593-2601 2018 Oct
Fatal extensive bone cement embolism: histological findings confirmed by Fourier transform infrared spectroscopy.
Forensic science international 2013 Jun 10;229;e23-5 2013 Jun 10
Bone cement implantation syndrome.
The Malaysian journal of pathology 2013 Jun;35;87-90 2013 Jun

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