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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Gadobutrol

2

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 13/12/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Gadolinium-based MRI contrast media
2

Publications

Acute respiratory distress syndrome after the use of gadolinium contrast agent.
Respiratory medicine case reports 2018;25;336-338 2018
Severe Acute Cardiopulmonary Failure Related to Gadobutrol Magnetic Resonance Imaging Contrast Reaction: Successful Resuscitation With Extracorporeal Membrane Oxygenation.
Mayo Clinic proceedings 2016 Mar;91;362-6 2016 Mar
Acute Respiratory Distress Syndrome after the Use of Gadolinium Contrast Media.
Yonsei medical journal 2015 Jul;56;1155-7 2015 Jul
Magnetic resonance imaging contrast agent related pulmonary edema: a case report.
European review for medical and pharmacological sciences 2012 Oct;16 Suppl 4;110-2 2012 Oct

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