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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Elinogrel

1

IX.h Dyspnea, unexplained otherwise

1
Last update : 17/10/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Viewpoint: reversible nature of platelet binding causing transfusion-related acute lung injury (TRALI) syndrome may explain dyspnea after ticagrelor and elinogrel.
Thrombosis and haemostasis 2012 Dec;108;1024-7 2012 Dec

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