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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Anesthetic agents (local, topical)

3

XI.a Cyanosis, a low SpO2 and normal measured PaO2

3
Last update : 17/02/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Articaine
1
Benzocaine (incl. topical)
4
Bupivacaine
1
Cetacaine
1
Lidocaine (lignocaine, xylocaine)
3
Nupercaine
1
Prilocaine
1
Tetracaine
1

Publications

Topical Benzocaine and Methemoglobinemia.
American journal of therapeutics 2017;24;e596-e598 2017
Methemoglobinemia in bronchoscopy: a case series and a review of the literature.
Journal of bronchology & interventional pulmonology 2013 Jul;20;241-6 2013 Jul
Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report.
Journal of medical case reports 2008 Jan 23;2;16 2008 Jan 23

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