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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Chlorhexidine

1

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 20/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Chlorhexidine-coated catheter(ization)
1

Publications

Severe and near-fatal anaphylactic reactions triggered by chlorhexidine-coated catheters in patients undergoing renal allograft surgery: a case series.
Canadian journal of anaesthesia = Journal canadien d'anesthesie 2019 Dec;66;1483-1488 2019 Dec
Anaphylaxis after disinfection with 2% chlorhexidine wand applicator.
BMJ case reports 2017 Aug 08;2017; 2017 Aug 08
Chlorhexidine anaphylaxis: case report and review of the literature.
Contact dermatitis 2004 Mar;50;113-6 2004 Mar
Immediate hypersensitivity to chlorhexidine: literature review.
European annals of allergy and clinical immunology 2004 Apr;36;123-6 2004 Apr

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