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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Influenza vaccine

2

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 08/09/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Vaccines
3

Publications

Wheeze as an adverse event in pediatric vaccine and drug randomized controlled trials: A systematic review.
Vaccine 2015 Oct 05;33;5333-5341 2015 Oct 05

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