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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Tocolytic therapy

3

II.a Pulmonary edema, noncardiogenic (NCPE)

3
Last update : 06/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beta-2 agonists, B2 mimetics (parenteral)
3
Magnesium sulfate
1
Ritodrine
2
Salbutamol - Albuterol
3
Terbutaline (parenteral)
2

Publications

A comparison of three tocolytics for preterm labor: a randomized clinical trial.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2014 May;27;801-6 2014 May
[Non-invasive ventilation for pulmonary edema associated with tocolytic agents during labour for a twin pregnancy].
Canadian journal of anaesthesia = Journal canadien d'anesthesie 2008 Nov;55;769-73 2008 Nov
The pathophysiology of pulmonary oedema with the use of beta-agonists.
BJOG : an international journal of obstetrics and gynaecology 2000 Apr;107;439-44 2000 Apr
Severe pulmonary edema associated with tocolytic therapy. Case report with hemodynamic study.
Intensive care medicine 1996 Nov;22;1280-1 1996 Nov
Chest case of the day. Pulmonary edema associated with tocolytic therapy.
AJR. American journal of roentgenology 1992 Jun;158;1356-7 1992 Jun
Pulmonary edema associated with tocolytic therapy.
Annals of internal medicine 1989 May 01;110;714-8 1989 May 01

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