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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nifedipine

2

XI.b Chest pain (acute or subacute), lone or prominent

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Verapamil
2

Publications

Do calcium antagonists contribute to gastro-oesophageal reflux disease and concomitant noncardiac chest pain?
British journal of clinical pharmacology 2007 Jul;64;83-9 2007 Jul
Drug-induced chest pain and myocardial infarction. Reports to a national centre and review of the literature.
European journal of clinical pharmacology 1997;53;105-10 1997

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