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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cyanoacrylate (N-butyl-2-cyanoacrylate-Histoacryl)

4

XVIII.g Eye-catcher: Cement (pulmonary) embolism

2
Last update : 28/03/2014
 
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Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Cement (bone cement, kyphoplasty, vertebroplasty)
5

Publications

Severe respiratory failure due to embolization of cyanoacrylate sclerosant.
QJM : monthly journal of the Association of Physicians 2014 Oct;107;831-2 2014 Oct
Acute pulmonary embolism following -butyl-cyanoacrylate endoscopic injection sclerotherapy.
Annals of gastroenterology 2012;25;261 2012
Cyanoacrylate in the treatment of gastric varices complicated by multiple pulmonary emboli.
Internal medicine journal 2006 Jul;36;462-5 2006 Jul
Fatal N-butyl-2-cyanoacrylate pulmonary embolism after sclerotherapy for variceal bleeding.
Endoscopy 2005 Jul;37;687 2005 Jul

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