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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Aspirin (Salicylate-ASA) - Aspirin containing drugs

5

XII.s Heart block (bundle branch- or AV-)

1
Last update : 17/09/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Altered mental status and complete heart block: an unusual presentation of aspirin toxicity.
BMJ case reports 2013 Jun 10;2013; 2013 Jun 10

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