Pneumotox » Drug » Aspirin (Salicylate-ASA) - Aspirin containing drugs » IV.f - Severe or catastrophic bronchospasm or asthma attack (can be fatal)

Aspirin (Salicylate-ASA) - Aspirin containing drugs

Tests to document AERD at PMID 17521312. Induction of tolerance/desensitization at PMID 23861151, 24369807

Last update : 06/01/2014

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment