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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Aspirin (Salicylate-ASA) - Aspirin containing drugs

5

II.b ARDS - Acute lung injury

2
Last update : 28/05/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Nonsteroidal anti-inflammatory drugs (NSAIDs)
5

Publications

Acute respiratory distress syndrome caused by salicylate intoxication.
Clinical case reports 2018 Sep;6;1905-1906 2018 Sep
Salicylate-induced pulmonary edema--a near-miss diagnosis.
The American journal of emergency medicine 2014 May;32;490.e5-6 2014 May
Current management of salicylate-induced pulmonary edema.
Southern medical journal 2011 Mar;104;225-32 2011 Mar
Recurrent ARDS in a 39-year-old woman with migraine headaches.
Chest 1998 Sep;114;919-22 1998 Sep
Late diagnosis of chronic salicylate intoxication.
Lancet (London, England) 1993 Sep 11;342;687 1993 Sep 11
Acute salicylate self-poisoning in 177 consecutive patients treated in ICU.
Acta anaesthesiologica Scandinavica 1987 May;31;312-6 1987 May
Bronchoalveolar lavage in recurrent aspirin-induced adult respiratory distress syndrome.
Chest 1986 Sep;90;452-3 1986 Sep
Adult respiratory distress syndrome induced by salicylate toxicity.
Postgraduate medicine 1985 Jul;78;117-9, 123 1985 Jul
Salicylate-induced pulmonary edema. Clinical features and prognosis.
Annals of internal medicine 1981 Oct;95;405-9 1981 Oct
Acute respiratory failure during therapy for salicylate intoxication.
Annals of emergency medicine 1981 Feb;10;104-6 1981 Feb
Fatal respiratory-distress syndrome and salicylate intoxication in a two-year-old.
Lancet (London, England) 1979 Nov 24;2;1131-2 1979 Nov 24

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