Pneumotox » Drug » Aspirin (Salicylate-ASA) - Aspirin containing drugs » II.a - Pulmonary edema, noncardiogenic (NCPE)

Aspirin (Salicylate-ASA) - Aspirin containing drugs

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II.a Pulmonary edema, noncardiogenic (NCPE)

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Systemic inflammatory response, MODS and pseudo-sepsis can be present. Measurement of salicylate levels in plasma instrumental to diagnose aspirin-related NCPE

Last update : 05/07/2014

Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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