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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Corticosteroids, inhaled (ICS)

5

XVII.h Nontuberculous pulmonary mycobacterial infection/superinfection

2
Last update : 04/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beclomethasone
2
Budesonide (inhaled)
3
Corticosteroids, systemic (oral, parenteral)
5
Fluticasone (inhaled - ICS)
4

Publications

Association between Inhaled Corticosteroid Use and Pulmonary Nontuberculous Mycobacterial Infection.
Annals of the American Thoracic Society 2018 Oct;15;1169-1176 2018 Oct
Chronic respiratory disease, inhaled corticosteroids and risk of non-tuberculous mycobacteriosis.
Thorax 2013 Mar;68;256-62 2013 Mar
Increased risk of nontuberculous mycobacterial infection in asthmatic patients using long-term inhaled corticosteroid therapy.
Respirology (Carlton, Vic.) 2012 Jan;17;185-90 2012 Jan

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