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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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  • Drugs
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Corticosteroids, inhaled (ICS)

5

XVII.k Bacterial (incl. Pseudomonas) airway colonization

2
Last update : 27/01/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Beclomethasone
2
Budesonide (inhaled)
3
Corticosteroids, systemic (oral, parenteral)
5
Fluticasone (inhaled - ICS)
4

Publications

Use of inhaled corticosteroids and risk of acquiring in patients with chronic obstructive pulmonary disease.
Thorax 2022 Jun;77;573-580 2022 Jun
Effect of inhaled corticosteroids on the microbiology of the respiratory tract.
Respirology (Carlton, Vic.) 2013 Feb;18;201-2 2013 Feb
Inhaled corticosteroids increase the risk of oropharyngeal colonization by Streptococcus pneumoniae in children with asthma.
Respirology (Carlton, Vic.) 2013 Feb;18;272-7 2013 Feb

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