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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Corticosteroids, inhaled (ICS)
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X.h
Eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
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Last update :
11/09/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Beclomethasone
Budesonide (inhaled)
Corticosteroids, systemic (oral, parenteral)
Fluticasone (inhaled - ICS)
Publications
Churg Strauss syndrome after introducing oral steroid to inhaler: a report of three cases.