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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Narcotics

4

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 14/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
Morphine
5

Publications

'Non-cardiogenic pulmonary edema after narcotic treatment for cancer pain,' by Bruera and Miller (Pain, 39 (1989) 297-300).
Pain 1990 Jul;42;125-126 1990 Jul
Non-cardiogenic pulmonary edema after narcotic treatment for cancer pain.
Pain 1989 Dec;39;297-300 1989 Dec
William Osler: narcotic-induced pulmonary edema.
The Journal of emergency medicine 1983;1;165-7 1983

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