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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Tofacitinib

2

XVII.e Pneumocystis jiroveci pneumonia

1
Last update : 22/03/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pneumonia after Initiation of Tofacitinib Therapy in Rheumatoid Arthritis: Case-Based Review.
Mediterranean journal of rheumatology 2019 Sep;30;167-170 2019 Sep
Atypical presentation of pneumonia in a patient with rheumatoid arthritis treated with tofacitinib: a case presentation.
BMC rheumatology 2018;2;34 2018

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