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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ustekinumab

1

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 25/07/2022
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Non-Infectious Pneumonitis and Acute Respiratory Distress Syndrome in a Patient on Ustekinumab Treatment: Case Report and Literature Review.
Life (Basel, Switzerland) 2024 Mar 16;14; 2024 Mar 16
Stelara struck: a case of noninfectious pneumonitis secondary to ustekinumab.
BMC pulmonary medicine 2022 Jul 19;22;280 2022 Jul 19

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