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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ustekinumab

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 01/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Ustekinumab associated chronic eosinophilic pneumonia.
The Journal of asthma : official journal of the Association for the Care of Asthma 2021 Dec;58;1670-1674 2021 Dec
61-Year-Old Man With Shortness of Breath and Cough.
Mayo Clinic proceedings 2021 Aug;96;2243-2247 2021 Aug
Association of Noninfectious Pneumonia With Ustekinumab Use.
JAMA dermatology 2019 Feb 01;155;221-224 2019 Feb 01
[Ustekinumab-induced eosinophilic pneumonia during the course of ustekinumab therapy for plaque psoriasis].
Annales de dermatologie et de venereologie 2015 Mar;142;193-6 2015 Mar
Psoriasis vulgaris complicated by eosinophilic pneumonia during ustekinumab treatment.
European journal of dermatology : EJD 2013;23;396-7 2013

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