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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Hydroxychloroquine

3

VI.b Pulmonary arterial hypertension

1
Last update : 01/07/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Chloroquine
3
Malaria prophylaxis
2
Mefloquine
1

Publications

Frequency of Long QT in Patients with SARS-CoV-2 Infection Treated with Hydroxychloroquine: A Meta-analysis.
International journal of antimicrobial agents 2020 Dec;56;106212 2020 Dec
Cardiac Complications Attributed to Chloroquine and Hydroxychloroquine: A Systematic Review of the Literature.
Drug safety 2018 Oct;41;919-931 2018 Oct

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