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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Herbals - Dietary botanical therapy - Health products/food - Plants

5

VI.b Pulmonary arterial hypertension

1
Last update : 20/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Amphetamine (and -derivatives)
3
Ayahuasca
1
Cyanide
5
Delphinium plant
3
Flavocoxid
2
Herbal extracts (via injection)
3
Herbals (fumigated, inhaled)
1
Kratom (Mitragynine)
1
Metals (heavy-)
4
Niacin
1
Poison hemlock
1
Sauropus androgynus
4
Scopolamine
2
Sibutramine
1
Tryptophan (l-tryptophan, synthetic)
5

Publications

Development of Pulmonary Arterial Hypertension in a Patient Treated with Qing-Dai (Chinese Herbal Medicine).
Internal medicine (Tokyo, Japan) 2019 Feb 01;58;395-399 2019 Feb 01
Chinese herbal medicine Qing-Dai-induced pulmonary arterial hypertension in a patient with ulcerative colitis: A case report and experimental investigation.
Respiratory medicine case reports 2019;26;265-269 2019
Chinese herbal drug natural indigo may cause pulmonary artery hypertension.
European heart journal 2016 Jul 01;37;1992 2016 Jul 01
Spontaneously remitted pulmonary arterial hypertension associated with the herbal medicine "bofutsushosan".
Internal medicine (Tokyo, Japan) 2013;52;1499-502 2013
Severe pulmonary hypertension possibly due to pyrrolizidine alkaloids in polyphytotherapy.
Swiss medical weekly 2009 Apr 04;139;210-1 2009 Apr 04

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