Pneumotox Online
v2.2
  • RSS Feed
  • Contact
  • News
  • Diagnosing DIRD
  • Browse
  • Available on AppStore Available on AppStore

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

  • Home
  • Browse by »
  • Drugs
  • Patterns

Alteplase (rTPA)

2

VIII.a Angioedema (may cause UAO, asphyxia and death)

1
Last update : 10/07/2012
 
Search
Advanced search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Angiotensin converting enzyme inhibitors (ACEI)
5
Tissue plasminogen activator (r-)
1

Publications

Angioedema After Use of Recombinant Tissue-Type Plasminogen Activators in Stroke.
Stroke 2024 Aug;55;2193-2197 2024 Aug
Angioedema after rt-PA infusion led to airway emergency: a case report of rescue treatment with fresh frozen plasma.
Brazilian journal of anesthesiology (Elsevier) 2023;73;223-226 2023
Angioedema Secondary to tPA Use in Acute Ischemic Stroke Patient with Hypertension: A Case Report.
Clinical practice and cases in emergency medicine 2021 May;5;159-162 2021 May
Hemilingual Angioedema after Thrombolysis in a Patient on an Angiotensin II Receptor Blocker.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2019 May;28;e44-e45 2019 May
Angioedema after thrombolysis with tissue plasminogen activator: an airway emergency.
Oxford medical case reports 2019 Jan;2019;omy112 2019 Jan
Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents.
Critical care research and practice 2018;2018;9360918 2018
A Novel Approach to the Treatment of Orolingual Angioedema After Tissue Plasminogen Activator Administration.
Annals of emergency medicine 2016 Sep;68;345-8 2016 Sep
Orolingual angiodema associated with alteplase treatment of acute stroke: a reappraisal.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2015 Jan;24;31-40 2015 Jan
Angioedema from recombinant TPA administration: case report and pathophysiology review.
American journal of therapeutics 2013;20;691-3 2013
Angioedema after tPA: what neurointensivists should know.
Neurocritical care 2012 Jun;16;440-3 2012 Jun
Lingual angioedema with macroglossia during the treatment of acute ischemic stroke with alteplase.
International journal of general medicine 2012;5;183-6 2012
[Orolingual angioedema under systemic thrombolysis with rt-PA: an underestimated side effect].
Der Nervenarzt 2009 Apr;80;459-63 2009 Apr
[Orolingual angioedema secondary to alteplase treatment in cases of stroke].
Revista de neurologia 2008 Mar 16-31;46;382 2008 Mar 16-31
[Angioneurotic orolingual edema associated with the use of rt-PA following a stroke].
Der Anaesthesist 2007 Oct;56;1024-7 2007 Oct
Biochemical basis of angioedema associated with recombinant tissue plasminogen activator treatment: an in vitro experimental approach.
Stroke 2002 Jun;33;1712-6 2002 Jun
Anaphylactoid reactions and angioedema during alteplase treatment of acute ischemic stroke.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 2000 May 02;162;1281-4 2000 May 02

Powered by

  • ^
  • Contact
  • Cookies
  • About

The Pneumotox website uses cookies. By accessing or using our website, you consent to the collection, use and disclosure of the garnered information in accordance with our privacy policy.

Learn more about cookies