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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carmustine (BCNU)

3

XVI.m Imaging: Interlobular septal thickening

1
Last update : 23/09/2018
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bendamustine
1
Fotemustine
1
Lomustine (CCNU)
3
Nitrosoureas (suffixes '-NU', '-mustine')
4

Publications

Radiologic evaluation of pulmonary injury following carmustine- and cyclophosphamide-based preparative regimen for autologous peripheral blood stem cell transplantation in children.
Pediatric radiology 2018 Dec;48;1875-1883 2018 Dec

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