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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Pramipexole
1
XII.a
Left or biventricular dysfunction/failure
1
Last update :
16/11/2014
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
Publications
Risk of heart failure following treatment with dopamine agonists in Parkinson's disease patients.
The risk of new onset heart failure associated with dopamine agonist use in Parkinson's disease.
Dopamine agonist use and the risk of heart failure.