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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methacrylate - Methylmethacrylate

2

VI.h Cement embolism

2
Last update : 29/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Polymethylmethacrylate cement pulmonary embolism and infarct.
Emergency medicine journal : EMJ 2014 Mar;31;257 2014 Mar
Fatal pulmonary embolism: when the cause is not a thrombus.
Spine 2012 Mar 15;37;E411-3 2012 Mar 15
Multiple fatal pulmonary embolism during polymethyl-methacrylate vertebroplasty with successful percutaneous retrieval of a large cement fragment.
Revista espanola de cardiologia (English ed.) 2012 Jun;65;571-2 2012 Jun
Pulmonary cement embolism associated with percutaneous vertebroplasty or kyphoplasty: a systematic review.
Orthopaedic surgery 2012 Aug;4;182-9 2012 Aug
Cement pulmonary embolism after percutaneous vertebroplasty and kyphoplasty: an overview.
Heart & lung : the journal of critical care 2012;41;509-11 2012
Pulmonary cement embolism after kyphoplasty.
Pain practice : the official journal of World Institute of Pain 2011;11;570-3 2011
[Multiple pulmonary embolism of cement after vertebroplasty].
Presse medicale (Paris, France : 1983) 2010 Mar;39;406-7 2010 Mar
Methylmethacrylate pulmonary emboli: radiographic and computed tomographic findings.
Journal of thoracic imaging 2009 Aug;24;241-7 2009 Aug
Delayed presentation of pulmonary polymethylmethacrylate emboli after percutaneous vertebroplasty.
Spine 2007 Sep 15;32;E589-93 2007 Sep 15
Linear pulmonary opacities in an asymptomatic patient.
Respiration; international review of thoracic diseases 2006;73;705-7 2006
Two patients with the same type of iatrogenic disease.
The European respiratory journal 2005 Feb;25;389-91 2005 Feb
[Pulmonary embolism of cement during vertebroplasty].
Annales francaises d'anesthesie et de reanimation 2004 Aug;23;827-30 2004 Aug
Successful management of a large pulmonary cement embolus after percutaneous vertebroplasty: a case report.
Spine 2003 Oct 15;28;E424-5 2003 Oct 15
Pulmonary embolism of polymethylmethacrylate after percutaneous vertebroplasty: a report of three cases.
Spine 2002 Oct 01;27;E416-8 2002 Oct 01

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