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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Methacrylate - Methylmethacrylate

2

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 06/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Acute bronchospasm associated with methylmethacrylate cement.
Anesthesiology 1998 Nov;89;1290-1 1998 Nov
Acute bronchospasm associated with polymethylmethacrylate cement.
Anesthesiology 1997 Sep;87;696-8 1997 Sep
Occupational asthma due to methylmethacrylate bone cement.
British medical journal (Clinical research ed.) 1986 Jul 19;293;207 1986 Jul 19

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