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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Benzodiazepines

5

II.q Respiratory distress or failure, not otherwise specified

1
Last update : 31/03/2019
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ethanol (ethyl alcohol, 'alcohol')
5
Midazolam
1

Publications

Benzodiazepines Associated With Acute Respiratory Failure in Patients With Obstructive Sleep Apnea.
Frontiers in pharmacology 2018;9;1513 2018

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