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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carbamazepine

3

X.m Vascultis (pulmonary, extrathoracic or systemic)-ANCA status unknown or negative)

1
Last update : 23/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Anticonvulsants
3

Publications

Carbamazepine hypersensitivity syndrome presenting as vasculitis of the CNS.
Journal of neurology, neurosurgery, and psychiatry 1999 Feb;66;249-50 1999 Feb

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