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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carbamazepine

3

XII.s Heart block (bundle branch- or AV-)

1
Last update : 06/11/2012
 
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Identify causative drugs
Diagnosing DIRD
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Drug and radiation history
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Drug singularity - Correct identification of the drug
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Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Anticonvulsants
3

Publications

Carbamazepine-induced cardiac dysfunction. Characterization of two distinct clinical syndromes.
Archives of internal medicine 1992 Jan;152;186-91 1992 Jan
Carbamazepine and cardiac conduction disturbances.
Annals of neurology 1987 Aug;22;280-1 1987 Aug
Cardiac complications of carbamazepine intoxication: treatment by haemoperfusion.
British medical journal (Clinical research ed.) 1983 Mar 26;286;1018 1983 Mar 26

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