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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Carbamazepine
3
XIII.b
Lymphoproliferative disease (pulmonary, endobronchial, endothoracic)
1
Last update :
17/08/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticonvulsants
Publications
[Pseudolymphoma induced by carbamazepine. Apropos of 2 cases].
Carbamazepine-induced pseudolymphoma and immune dysregulation.
Lymphoproliferative disorders associated with carbamazepine.