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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carbamazepine

3

X.d Lupus - Lupus syndrome (see also Vd)

2
Last update : 11/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticonvulsants
3

Publications

Do selected drugs increase the risk of lupus? A matched case-control study.
British journal of clinical pharmacology 2010 Oct;70;588-96 2010 Oct
[Chest pain, reduced physical activity, and polyserositis in a 35-year old patient with anticonvulsive medication].
Der Internist 2006 Jan;47;69-75 2006 Jan
[Carbamazepine-induced systemic lupus erythematosus--a case report].
Neurologia i neurochirurgia polska 2006;40;151-5 2006
Lupus and pulmonary nodules consistent with bronchiolitis obliterans organizing pneumonia induced by carbamazepine.
Mayo Clinic proceedings 1997 Dec;72;1145-7 1997 Dec
A case of drug induced lupus due to carbamazepine.
The Journal of rheumatology 1987 Jun;14;599-600 1987 Jun

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