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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Carbamazepine

3

V.d Pleural/pericardial effusion, ANA positive (DI lupus)

1
Last update : 10/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anticonvulsants
3

Publications

[Chest pain, reduced physical activity, and polyserositis in a 35-year old patient with anticonvulsive medication].
Der Internist 2006 Jan;47;69-75 2006 Jan
Carbamazepine-induced systemic lupus erythematosus presenting as cardiac tamponade.
Chest 2000 Feb;117;597-8 2000 Feb
Carbamazepine-induced systemic lupus erythematosus.
Clinical neuropharmacology 1989 Apr;12;115-8 1989 Apr
Carbamazepine induced systemic lupus erythematosus: case report.
British medical journal (Clinical research ed.) 1985 Sep 07;291;632-3 1985 Sep 07

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