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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Fresh frozen plasma

2

II.h Overload pulmonary edema (including posttransfusional (TACO))

1
Last update : 13/12/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Dose-associated pulmonary complication rates after fresh frozen plasma administration for warfarin reversal.
Journal of thrombosis and haemostasis : JTH 2016 Feb;14;324-30 2016 Feb

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