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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Transhepatic arterial chemoembolization (TACE)

3

II.b ARDS - Acute lung injury

3
Last update : 27/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Doxorubicin - Adriamycin
3
Lipiodol - Iodinated/iodized oil (RCM)
2
Transcatheter embolization
2

Publications

Safety and efficacy of intra-arterial hepatic chemotherapy with doxorubicin-loaded nanoparticles in hepatocellular carcinoma.
ESMO open 2017;2;e000238 2017
Lipiodol embolism following transarterial chemoembolization: an atypical case.
Critical care medicine 2014 Jun;42;e481-4 2014 Jun
Acute lung injury following transcatheter hepatic arterial chemoembolization of doxorubicin-loaded LC beads in a patient with hepatocellular carcinoma.
Lung India : official organ of Indian Chest Society 2012 Apr;29;169-72 2012 Apr
Chemoembolization of hepatocellular carcinoma with drug-eluting beads complicated by interstitial pneumonitis.
Seminars in interventional radiology 2011 Jun;28;218-21 2011 Jun
Pulmonary complications after hepatic artery chemoembolization or infusion via the inferior phrenic artery for primary liver cancer.
Journal of vascular and interventional radiology : JVIR 2002 Sep;13;893-900 2002 Sep
Pulmonary oil embolism after transcatheter oily chemoembolization of hepatocellular carcinoma.
Radiology 1993 Jun;187;689-93 1993 Jun

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