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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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GnRH

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

1
Last update : 20/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

A patient developing anaphylaxis and sensitivity to two different GnRH analogues and a review of literature.
Journal of pediatric endocrinology & metabolism : JPEM 2015 Jul;28;923-5 2015 Jul
Recurrent anaphylaxis associated with gonadotropin-releasing hormone analogs: case report and review of the literature.
Pharmacotherapy 2006 Dec;26;1811-5 2006 Dec
Recurrent anaphylaxis to a depot form of GnRH analogue.
Obstetrics and gynecology 1991 Nov;78;943-6 1991 Nov

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