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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Matuzumab

1

IV.a Bronchospasm - Wheezing - Asthma

1
Last update : 17/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary complications of novel antineoplastic agents for solid tumors.
Chest 2008 Feb;133;528-38 2008 Feb
A phase I study of the humanized monoclonal anti-epidermal growth factor receptor (EGFR) antibody EMD 72000 (matuzumab) in combination with paclitaxel in patients with EGFR-positive advanced non-small-cell lung cancer (NSCLC).
Annals of oncology : official journal of the European Society for Medical Oncology 2006 Jun;17;1007-13 2006 Jun

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