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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Captopril

4

XII.al Hyperkinetic circulation

1
Last update : 12/05/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Hyperkinetic circulation associated with captopril therapy for congestive heart failure.
The New England journal of medicine 1981 Aug 13;305;405-6 1981 Aug 13

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