Pneumotox » Drug » Chemicals » IV.c - Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

Chemicals

5

IV.c Obliterative bronchiolitis (a pattern consistent with) (see also IVn, XVx)

3

Notably diacetyl, a butter flavoring agent used in the food industry

Last update : 28/01/2013

Diagnosing DIRD

1

Drug and radiation history

2

Drug singularity - Correct identification of the drug

3

Consistent timing of exposure v. onset of symptoms

4

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

5

Careful exlusion of another cause

6

Remission of symptoms with removal of drug

7

Recurrence with rechallenge (rarely advisable)

8

Causality assessment

More detailed checklist

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