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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Ipilimumab

4

X.o Neutrophilic dermatosis (Pyoderma, Sweet syndrome)

1
Last update : 20/10/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
CTLA4 blocking immunotherapy
3
Immune checkpoint inhibitors (ICI) - ICI combinatorial Rx
5
Tremelimumab
1

Publications

Sweet's syndrome in a patient with metastatic melanoma after ipilimumab therapy.
Melanoma research 2013 Dec;23;498-501 2013 Dec

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