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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Calcium replacement therapy

1

I.i Diffuse pulmonary calcification (calciphylaxis)

1
Last update : 10/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Diffuse high-attenuation pulmonary abnormalities: a pattern-oriented diagnostic approach on high-resolution CT.
AJR. American journal of roentgenology 2005 Jan;184;273-82 2005 Jan
Metastatic pulmonary calcifications after cardiac surgery in children.
Radiology 1990 Feb;174;463-7 1990 Feb
Pathological calcification of the lungs following intravenous administration of calcium.
The American journal of medicine 1960 Aug;29;363-8 1960 Aug

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