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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Highly active antiretroviral therapy - HAART

3

X.k Sarcoid-like granulomatosis (endo-/extrathoracic)

1
Last update : 05/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abacavir
2
Dolutegravir
1
Sofosbuvir
1

Publications

Drug-Induced Sarcoidosis-Like Reactions.
Chest 2018 Sep;154;664-677 2018 Sep
CT-histologic correlation of the ATS/ERS 2002 classification of idiopathic interstitial pneumonias.
Radiographics : a review publication of the Radiological Society of North America, Inc 2003;23;1057-71 2003
Newly diagnosed pulmonary sarcoidosis in HIV-infected patients.
Radiology 2001 Jan;218;242-6 2001 Jan
Sarcoid-like pulmonary disorder in human immunodeficiency virus-infected patients receiving antiretroviral therapy.
American journal of respiratory and critical care medicine 1999 Jun;159;2009-13 1999 Jun

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