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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dyes

3

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

2
Last update : 30/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Black stone (para-phenylenediamine)
1
Fluorescein
1
Indigo
1
Indigo-indirubin
1
Methylene blue
1
Patent blue
2
Sudan red dye
1

Publications

Images in clinical medicine. Anaphylaxis associated with blue dye.
The New England journal of medicine 2012 Nov 22;367;2026 2012 Nov 22
Anaphylaxis to patent blue V: a case series and proposed diagnostic protocol.
Allergy 2010 Mar;65;396-400 2010 Mar
Biphasic anaphylactic reaction to blue dye during sentinel lymph node biopsy.
World journal of surgical oncology 2008 Jul 27;6;79 2008 Jul 27
Near-fatal anaphylaxis to patent blue V.
The British journal of dermatology 2004 May;150;1037-8 2004 May
Toxicity of Food Drug and Cosmetic Blue No. 1 dye in critically ill patients.
Chest 2004 Feb;125;793-5 2004 Feb
Anaphylactic reaction to methylene blue dye after laparoscopic chromopertubation.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 2003 Apr;81;71-2 2003 Apr
Anaphylactic/anaphylactoid reaction to contrast dye administered in the ureter.
Journal of clinical anesthesia 1993;5;510-2 1993
Hazards of intravenous indigo carmine, fluorescein, and methylene blue.
Texas medicine 1980 Oct;76;49-51 1980 Oct

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