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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Status post-hematopoietic stem cell (HSCT) or bone marrow transplantation (BMT)

5

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 28/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Non-infectious pulmonary complications after the hematopoietic stem cell transplantation].
Revista portuguesa de pneumologia 2010;16;815-28 2010
Non-infectious pulmonary complications after bone marrow transplantation.
Postgraduate medical journal 2002 May;78;257-62 2002 May
Chest radiographic features of engraftment syndrome.
Journal of thoracic imaging 2000 Jan;15;56-60 2000 Jan
Engraftment syndrome and survival after respiratory failure post-bone marrow transplantation.
Intensive care medicine 1998 Jul;24;732-5 1998 Jul

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