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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Mephenidate (Methylphenidate)

2

VI.g Foreign body pulmonary vasculopathy (Excipient lung disease)

1
Last update : 28/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Abused drugs/substances (illicit-, street drugs - IV/inhaled)
5

Publications

Recurrence of intravenous talc granulomatosis following single lung transplantation.
Canadian respiratory journal 1998;5;511-4 1998
Panlobular emphysema in young intravenous Ritalin abusers.
The American review of respiratory disease 1991 Mar;143;649-56 1991 Mar
The pulmonary vascular lesions of intravenous drug abuse.
Human pathology 1980 Mar;11;133-45 1980 Mar
Self-induced pulmonary granulomatosis. A consequence of intravenous injection of drugs intended for oral use.
Chest 1980 Jul;78;90-4 1980 Jul
67Gallium scanning in talc-induced pulmonary granulomatosis.
Chest 1980 Apr;77;561-5 1980 Apr

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