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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amphetamine (and -derivatives)

3

VI.b Pulmonary arterial hypertension

1
Last update : 05/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Dextroamphetamine
1
Fluoroamphetamine
1
Methamphetamine
5
Sibutramine
1

Publications

Is methamphetamine use associated with idiopathic pulmonary arterial hypertension?
Chest 2006 Dec;130;1657-63 2006 Dec
A 44-yr-old male with progressive dyspnoea and dry cough.
The European respiratory journal 2002 Sep;20;786-8 2002 Sep
Stimulant-induced pulmonary toxicity.
Chest 1995 Oct;108;1140-9 1995 Oct

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