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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Busulfan

5

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

2
Last update : 10/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Busulfan + Melphalan regimen
1

Publications

Organizing pneumonia: chest HRCT findings.
Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia 2015;41;231-7 2015
Drug-associated organizing pneumonia: high-resolution CT findings in 9 patients.
Journal of thoracic imaging 2006 Mar;21;22-6 2006 Mar
Organizing pneumonia: typical and atypical HRCT patterns.
La Radiologia medica 2006 Mar;111;202-12 2006 Mar
[Alveolar opacities and busulfan pneumonia].
Revue des maladies respiratoires 1993;10;39-41 1993
Busulfan lung. Report of two cases and review of the literature.
The American journal of roentgenology, radium therapy, and nuclear medicine 1974 Jan;120;151-6 1974 Jan
Diagnosis of busulfan lung by transcatheter biopsy.
Chest 1973 Dec;64;771-3 1973 Dec
Busulphan lung.
Thorax 1968 Mar;23;187-93 1968 Mar

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