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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy to the chest

5

XI.ag Vertebral compression fracture

1
Last update : 22/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy (endobronchial brachytherapy)
2
Radiation therapy (medium term & late effects)
5
Radiation therapy to the breast
4
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5
Radioactive seeds
2

Publications

Analysis of the Factors Contributing to Vertebral Compression Fractures After Spine Stereotactic Radiosurgery.
International journal of radiation oncology, biology, physics 2017 Feb 01;97;236-245 2017 Feb 01
Vertebral compression fracture (VCF) after spine stereotactic body radiation therapy (SBRT): analysis of predictive factors.
International journal of radiation oncology, biology, physics 2012 Nov 01;84;e343-9 2012 Nov 01
Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases.
Journal of neurosurgery. Spine 2012 Apr;16;379-86 2012 Apr

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