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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy to the chest

5

XII.s Heart block (bundle branch- or AV-)

1
Last update : 20/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy (endobronchial brachytherapy)
2
Radiation therapy (medium term & late effects)
5
Radiation therapy to the breast
4
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5
Radioactive seeds
2

Publications

Long-Term Radiotherapy-Induced Cardiac Complications: A Case Report.
The American journal of case reports 2019 Aug 11;20;1182-1188 2019 Aug 11
Complete atrioventricular block following mediastinal irradiation: a report of six cases.
Pacing and clinical electrophysiology : PACE 1991 Jul;14;1112-8 1991 Jul

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